| Protein Name | pro-platelet basic protein |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5473 |
| Gene Symbol | PPBP |
| UniProt | P02775 (CXCL7_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
339
Total Number of Articles : 407 |
Description |
pro-platelet basic protein |
| Gene Summary |
The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014] |
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| Properties | |