| Protein Name | lipoprotein lipase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24539 |
| Gene Symbol | Lpl |
| UniProt | Q06000 (LIPL_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
431
Total Number of Articles : 710 |
Description |
lipoprotein lipase |
| Gene Summary |
Enables lipoprotein lipase activity and triglyceride binding activity. Involved in several processes, including lipid catabolic process; negative regulation of cellular response to insulin stimulus; and triglyceride biosynthetic process. Located in extracellular space. Used to study abdominal obesity-metabolic syndrome 1; familial hyperlipidemia; metabolic dysfunction-associated steatotic liver disease; and obesity. Biomarker of end stage renal disease; focal segmental glomerulosclerosis; metabolic dysfunction-associated steatotic liver disease; obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Alzheimer's disease; artery disease (multiple); familial hyperlipidemia (multiple); muscular disease; and type 2 diabetes mellitus. Orthologous to human LPL (lipoprotein lipase). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |