| Protein Name | prohibitin 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12034 |
| Gene Symbol | Phb2 |
| UniProt | O35129 (PHB2_MOUSE), Q3V235 (Q3V235_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
112
Total Number of Articles : 101 |
Description |
prohibitin 2 |
| Gene Summary |
Enables sphingolipid binding activity. Involved in several processes, including positive regulation of non-canonical NF-kappaB signal transduction; regulation of cytochrome-c oxidase activity; and regulation of gene expression. Acts upstream of or within several processes, including mammary gland development; negative regulation of intracellular estrogen receptor signaling pathway; and negative regulation of mammary gland epithelial cell proliferation. Located in cell surface; mitochondrial inner membrane; and nucleus. Part of mitochondrial prohibitin complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and respiratory system. Orthologous to human PHB2 (prohibitin 2). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |