| Protein Name | xeroderma pigmentosum, complementation group A |
|---|---|
| Organism | Mus musculus |
| Gene ID | 22590 |
| Gene Symbol | Xpa |
| UniProt | Q64267 (XPA_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
51
Total Number of Articles : 47 |
Description |
xeroderma pigmentosum, complementation group A |
| Gene Summary |
Predicted to enable DNA binding activity; protein domain specific binding activity; and protein homodimerization activity. Acts upstream of or within several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; nucleotide-excision repair; and positive regulation of transcription initiation by RNA polymerase II. Located in nucleus. Is expressed in forelimb bud. Used to study xeroderma pigmentosum group A. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group A. Orthologous to human XPA (XPA, DNA damage recognition and repair factor). [provided by Alliance of Genome Resources, May 2025] |
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