| Protein Name | Dual oxidase |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 33477 |
| Gene Symbol | Duox |
| UniProt | Q9VQH2 (DUOX_DROME), M9PCF1 (M9PCF1_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
16
Total Number of Articles : 22 |
Description |
Dual oxidase |
| Gene Summary |
Enables NAD(P)H oxidase H2O2-forming activity; peroxidase activity; and superoxide-generating NADPH oxidase activity. Involved in several processes, including adult chitin-based cuticle development; adult chitin-containing cuticle pigmentation; and imaginal disc-derived wing morphogenesis. Located in endomembrane system. Is expressed in adult head and embryonic/larval fat body. Used to study primary bacterial infectious disease. Human ortholog(s) of this gene implicated in congenital hypothyroidism and thyroid dyshormonogenesis 6. Orthologous to several human genes including DUOX2 (dual oxidase 2). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |