Protein Name cholecystokinin B receptor
Organism Rattus norvegicus
Gene ID 25706
Gene Symbol

Cckbr

UniProt P30553 (GASR_RAT)
Relationships Total Number of functionally related compound(s) : 159
Total Number of Articles : 181
Description

cholecystokinin B receptor

Gene Summary

Cholecystokinin was one of the first gastrointestinal peptides discovered in the mammalian brain. Cholecystokinin receptors are members of the G protein-coupled receptor superfamily, stimulating phosphatidylinositol turnover and intracellular calcium mobilization. This gene encodes a cholecystokinin receptor of the B subtype. These receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. [provided by RefSeq, Jul 2008]

synonyms
  • gastrin/cholecystokinin type B receptor
  • CCK-B receptor
  • CCK-BR
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Properties