| Protein Name | leukotriene C4 synthase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4056 |
| Gene Symbol | LTC4S |
| UniProt | Q16873 (LTC4S_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
117
Total Number of Articles : 160 |
Description |
leukotriene C4 synthase |
| Gene Summary |
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq, Jul 2008] |
| synonyms |
|
| Properties | |