Protein Name Fc epsilon receptor Ia
Organism Homo sapiens
Gene ID 2205
Gene Symbol

FCER1A

UniProt P12319 (FCERA_HUMAN)
Relationships Total Number of functionally related compound(s) : 250
Total Number of Articles : 359
Description

Fc epsilon receptor Ia

Gene Summary

The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]

synonyms
  • high affinity immunoglobulin epsilon receptor subunit alpha
  • Fc IgE receptor, alpha polypeptide
  • Fc epsilon RI alpha-chain
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Properties