Protein Name Carboxylesterase type B domain-containing protein;Neuroligin-1
Organism Caenorhabditis elegans
Gene ID 181484
Gene Symbol

nlg-1

UniProt Q9XTG1 (NLGN1_CAEEL), A0A0K3AVG1 (A0A0K3AVG1_CAEEL), G5ECG6 (G5ECG6_CAEEL), A0A0K3AVK6 (A0A0K3AVK6_CAEEL), A0A0K3AT61 (A0A0K3AT61_CAEEL), A0A0K3AT91 (A0A0K3AT91_CAEEL), G5EED7 (G5EED7_CAEEL)
Relationships Total Number of functionally related compound(s) : 10
Total Number of Articles : 8
Description

Carboxylesterase type B domain-containing protein;Neuroligin-1

Gene Summary

Predicted to enable neurexin family protein binding activity and signaling receptor activity. Involved in gamma-aminobutyric acid receptor clustering and negative regulation of neurotransmitter secretion. Located in axon; dendrite; and synapse. Is expressed in body wall musculature; diagonal muscle; head; nervous system; and tail. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to several human genes including NLGN4Y (neuroligin 4 Y-linked). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • Carboxylesterase type B domain-containing protein;Neuroligin-1
  • CELE_C40C9.5
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Properties