| Protein Name | superoxide dismutase 2, mitochondrial |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20656 |
| Gene Symbol | Sod2 |
| UniProt | P09671 (SODM_MOUSE), Q4FJX9 (Q4FJX9_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
455
Total Number of Articles : 740 |
Description |
superoxide dismutase 2, mitochondrial |
| Gene Summary |
Enables superoxide dismutase activity. Acts upstream of or within several processes, including acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure; apoptotic signaling pathway; and erythrophore differentiation. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Used to study Canavan disease; Leigh disease; amyotrophic lateral sclerosis type 1; congestive heart failure; and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); cardiomyopathy (multiple); liver disease (multiple); and optic nerve disease (multiple). Orthologous to human SOD2 (superoxide dismutase 2). [provided by Alliance of Genome Resources, May 2025] |
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