Protein Name | superoxide dismutase 1, soluble |
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Organism | Mus musculus |
Gene ID | 20655 |
Gene Symbol | Sod1 |
UniProt | P08228 (SODC_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
689
Total Number of Articles : 1147 |
Description |
superoxide dismutase 1, soluble |
Gene Summary |
Enables superoxide dismutase activity. Involved in axonal transport; negative regulation of inflammatory response; and positive regulation of phagocytosis. Acts upstream of or within several processes, including action potential initiation; determination of adult lifespan; and neurogenesis. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study amyotrophic lateral sclerosis type 1; dry eye syndrome; and low tension glaucoma. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; artery disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and neurodegenerative disease (multiple). Orthologous to human SOD1 (superoxide dismutase 1). [provided by Alliance of Genome Resources, May 2025] |
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