Protein Name eukaryotic translation elongation factor 2
Organism Rattus norvegicus
Gene ID 29565
Gene Symbol

Eef2

UniProt P05197 (EF2_RAT)
Relationships Total Number of functionally related compound(s) : 110
Total Number of Articles : 88
Description

eukaryotic translation elongation factor 2

Gene Summary

Enables several functions, including 5S rRNA binding activity; actin filament binding activity; and p53 binding activity. Involved in several processes, including cellular response to brain-derived neurotrophic factor stimulus; positive regulation of cytoplasmic translation; and response to ischemia. Located in cytoplasm and ribosome. Part of ribonucleoprotein complex. Is active in glutamatergic synapse. Human ortholog(s) of this gene implicated in glaucoma; spinocerebellar ataxia type 26; and stomach cancer. Orthologous to human EEF2 (eukaryotic translation elongation factor 2). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • elongation factor 2
  • Ef-2
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Properties