CPRiL

TGM2

transglutaminase 2

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• protein-glutamine gamma-glutamyltransferase 2
• C polypeptide, protein-glutamine-gamma-glutamyltransferase
• TGase C
TGase H
TGase II
TGase-2
erythrocyte transglutaminase
heart G alpha(h)
hhG alpha(h)
isopeptidase TGM2
protein G alpha(h)
protein-glutamine deamidase TGM2
protein-glutamine dopaminyltransferase TGM2
protein-glutamine histaminyltransferase TGM2
protein-glutamine noradrenalinyltransferase TGM2
protein-glutamine serotonyltransferase TGM2
tTgase
tissue transglutaminase
transglutaminase C
transglutaminase H
transglutaminase II
G(h)
TG(C)
TGC
hTG2
tTG