Protein Name interleukin 6
Organism Rattus norvegicus
Gene ID 24498
Gene Symbol

Il6

UniProt P20607 (IL6_RAT)
Relationships Total Number of functionally related compound(s) : 2269
Total Number of Articles : 4916
Description

interleukin 6

Gene Summary

Enables cytokine activity and interleukin-6 receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of cell communication; and positive regulation of metabolic process. Located in extracellular space. Used to study several diseases, including acute necrotizing pancreatitis; disseminated intravascular coagulation; hypertension (multiple); impotence; and steatotic liver disease. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); auditory system disease (multiple); liver disease (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); liver disease (multiple); and periodontal disease (multiple). Orthologous to human IL6 (interleukin 6). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • interleukin-6
  • IL-6
  • Interleukin 6 (interferon, beta 2)
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Properties