Protein Name pyruvate carboxylase
Organism Rattus norvegicus
Gene ID 25104
Gene Symbol

Pc

UniProt P52873 (PYC_RAT)
Relationships Total Number of functionally related compound(s) : 415
Total Number of Articles : 484
Description

pyruvate carboxylase

Gene Summary

Enables biotin binding activity and pyruvate carboxylase activity. Involved in gluconeogenesis and positive regulation of phospholipid biosynthetic process. Predicted to be located in cytosol. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in pyruvate carboxylase deficiency disease. Orthologous to human PC (pyruvate carboxylase). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • pyruvate carboxylase, mitochondrial
  • PCB
  • pyruvic carboxylase
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Properties