Protein Name macrophage migration inhibitory factor
Organism Homo sapiens
Gene ID 4282
Gene Symbol

MIF

UniProt P14174 (MIF_HUMAN), I4AY87 (I4AY87_HUMAN)
Relationships Total Number of functionally related compound(s) : 593
Total Number of Articles : 699
Description

macrophage migration inhibitory factor

Gene Summary

This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]

synonyms
  • macrophage migration inhibitory factor
  • L-dopachrome isomerase
  • L-dopachrome tautomerase
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Properties