| Protein Name | glycerol 2-dehydrogenase (NADP(+)) GCY1 |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 854287 |
| Gene Symbol | GCY1 |
| UniProt | P14065 (GCY1_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
14
Total Number of Articles : 11 |
Description |
glycerol 2-dehydrogenase (NADP(+)) GCY1 |
| Gene Summary |
Enables aldose reductase (NADPH) activity; glycerol dehydrogenase [NAD(P)+] activity; and mRNA binding activity. Involved in cellular response to oxidative stress; glycerol to glycerone phosphate metabolic process; and pentose catabolic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including 46,XY sex reversal 8; alcohol dependence; congenital bile acid synthesis defect 2; leukemia (multiple); and type 2 diabetes mellitus. Orthologous to several human genes including AKR1A1 (aldo-keto reductase family 1 member A1); AKR1B1 (aldo-keto reductase family 1 member B); and AKR1B10 (aldo-keto reductase family 1 member B10). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |