Protein Name N-ethylmaleimide sensitive factor, vesicle fusing ATPase
Organism Homo sapiens
Gene ID 4905
Gene Symbol

NSF

UniProt P46459 (NSF_HUMAN), A0A384MTI6 (A0A384MTI6_HUMAN)
Relationships Total Number of functionally related compound(s) : 120
Total Number of Articles : 192
Description

N-ethylmaleimide sensitive factor, vesicle fusing ATPase

Gene Summary

Enables PDZ domain binding activity and ionotropic glutamate receptor binding activity. Involved in intracellular protein transport; positive regulation of protein catabolic process; and positive regulation of receptor recycling. Located in Golgi apparatus; cytosol; and plasma membrane. Implicated in developmental and epileptic encephalopathy 96. [provided by Alliance of Genome Resources, May 2025]

synonyms
  • vesicle-fusing ATPase
  • N-ethylmaleimide-sensitive factor-like protein
  • N-ethylmaleimide-sensitive fusion protein
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Properties