| Protein Name | thrombomodulin |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 83580 |
| Gene Symbol | Thbd |
| UniProt | O35370 (O35370_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
37
Total Number of Articles : 37 |
Description |
thrombomodulin |
| Gene Summary |
Predicted to enable signaling receptor activity. Involved in response to X-ray; response to cAMP; and response to lipopolysaccharide. Located in apicolateral plasma membrane; extracellular space; and vacuolar membrane. Used to study acute kidney failure. Biomarker of adult respiratory distress syndrome; hypertension; ischemia; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |