| Protein Name | Death-associated inhibitor of apoptosis 1 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 39753 |
| Gene Symbol | Diap1 |
| UniProt | Q24306 (DIAP1_DROME), M9PI74 (M9PI74_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
26
Total Number of Articles : 24 |
Description |
Death-associated inhibitor of apoptosis 1 |
| Gene Summary |
Enables several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; enzyme binding activity; and ubiquitin-like protein ligase activity. Involved in several processes, including germ cell development; protein modification by small protein conjugation; and regulation of signal transduction. Located in nucleus and perinuclear region of cytoplasm. Is expressed in several structures, including Malpighian tubule primordium; ganglia; germline cell; head epidermis primordium; and imaginal disc. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2; breast cancer; carcinoma (multiple); extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue; and prostate cancer. Orthologous to human XIAP (X-linked inhibitor of apoptosis); BIRC2 (baculoviral IAP repeat containing 2); and BIRC3 (baculoviral IAP repeat containing 3). [provided by Alliance of Genome Resources, May 2025] |
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