| Protein Name | insulin receptor |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24954 |
| Gene Symbol | Insr |
| UniProt | T2CB11 (T2CB11_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
408
Total Number of Articles : 704 |
Description |
insulin receptor |
| Gene Summary |
Enables several functions, including enzyme binding activity; insulin binding activity; and insulin receptor activity. Involved in several processes, including neuron projection organization; protein phosphorylation; and regulation of primary metabolic process. Located in several cellular components, including dendrite membrane; external side of plasma membrane; and neuronal cell body membrane. Used to study chronic kidney disease; diabetic neuropathy; liver disease (multiple); and type 2 diabetes mellitus. Biomarker of several diseases, including Alzheimer's disease; diabetes mellitus (multiple); hepatic encephalopathy; liver disease (multiple); and short bowel syndrome. Human ortholog(s) of this gene implicated in Donohue syndrome; glucose metabolism disease (multiple); and reproductive organ cancer (multiple). Orthologous to human INSR (insulin receptor). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |