CPRiL

Protein Name	X-linked inhibitor of apoptosis
Organism	Rattus norvegicus
Gene ID	63879
Gene Symbol	Xiap
UniProt	Q9R0I6 (XIAP_RAT)
Relationships	Total Number of functionally related compound(s) : 89 Total Number of Articles : 75
Description	X-linked inhibitor of apoptosis
Gene Summary	Enables protease binding activity and scaffold protein binding activity. Involved in cellular response to hydrogen peroxide and negative regulation of neuron apoptotic process. Located in perinuclear region of cytoplasm. Part of protein-containing complex. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Orthologous to several human genes including XIAP (X-linked inhibitor of apoptosis). [provided by Alliance of Genome Resources, May 2025]
synonyms	E3 ubiquitin-protein ligase XIAP IAP homolog A IAP-3 RIAP-3 RING-type E3 ubiquitin transferase XIAP X-linked IAP X-linked inhibitor of apoptosis protein X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase apoptosis inhibitor protein 3 baculoviral IAP repeat-containing 4 baculoviral IAP repeat-containing protein 4 inhibitor of apoptosis protein 3 Api3 Birc4 riap3 Click to show/hide the synonyms
Properties