Protein Name transforming growth factor alpha
Organism Rattus norvegicus
Gene ID 24827
Gene Symbol

Tgfa

UniProt P01134 (TGFA_RAT), U5LKN7 (U5LKN7_RAT)
Relationships Total Number of functionally related compound(s) : 487
Total Number of Articles : 532
Description

transforming growth factor alpha

Gene Summary

Enables epidermal growth factor receptor binding activity. Involved in several processes, including hepatocyte proliferation; negative regulation of apoptotic process; and positive regulation of cell population proliferation. Located in extracellular space. Used to study pancreatic cancer. Biomarker of acute kidney failure and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in gastroenteritis. Orthologous to human TGFA (transforming growth factor alpha). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • protransforming growth factor alpha
  • RATTGFAA
  • TGFAA
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Properties