| Protein Name | adenosine A1 receptor |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 29290 |
| Gene Symbol | Adora1 |
| UniProt | P25099 (AA1R_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
132
Total Number of Articles : 149 |
Description |
adenosine A1 receptor |
| Gene Summary |
Enables several functions, including G protein-coupled adenosine receptor activity; G-protein beta/gamma-subunit complex binding activity; and heterotrimeric G-protein binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of lipid catabolic process; and regulation of secretion. Located in several cellular components, including axon; basolateral plasma membrane; and presynaptic active zone. Is active in calyx of Held; postsynaptic membrane; and presynaptic membrane. Used to study cerebral infarction; hypertension; lung disease; and obstructive sleep apnea. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADORA1 (adenosine A1 receptor). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |