Protein Name F2R like thrombin or trypsin receptor 3
Organism Homo sapiens
Gene ID 9002
Gene Symbol

F2RL3

UniProt Q96RI0 (PAR4_HUMAN)
Relationships Total Number of functionally related compound(s) : 107
Total Number of Articles : 93
Description

F2R like thrombin or trypsin receptor 3

Gene Summary

This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016]

synonyms
  • proteinase-activated receptor 4
  • F2R like thrombin/trypsin receptor 3
  • PAR-4
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Properties