| Protein Name | glutamate-ammonia ligase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24957 |
| Gene Symbol | Glul |
| UniProt | P09606 (GLNA_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
345
Total Number of Articles : 681 |
Description |
glutamate-ammonia ligase |
| Gene Summary |
Enables several functions, including anion binding activity; dynein light chain binding activity; and metal ion binding activity. Involved in glutamine metabolic process; positive regulation of cell communication; and positive regulation of epithelial cell proliferation. Located in axon terminus; myelin sheath; and perikaryon. Part of protein-containing complex. Used to study epilepsy; obesity; and temporal lobe epilepsy. Biomarker of diabetic retinopathy; middle cerebral artery infarction; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in congenital glutamine deficiency; epilepsy (multiple); heart disease; and neurodegenerative disease (multiple). Orthologous to human GLUL (glutamate-ammonia ligase). [provided by Alliance of Genome Resources, May 2025] |
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