Protein Name | carbohydrate sulfotransferase 15 |
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Organism | Homo sapiens |
Gene ID | 51363 |
Gene Symbol | CHST15 |
UniProt | Q7LFX5 (CHSTF_HUMAN), B4DH74 (B4DH74_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
49
Total Number of Articles : 31 |
Description |
carbohydrate sulfotransferase 15 |
Gene Summary |
Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012] |
synonyms |
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Properties | |