Protein Name carbohydrate sulfotransferase 15
Organism Homo sapiens
Gene ID 51363
Gene Symbol

CHST15

UniProt Q7LFX5 (CHSTF_HUMAN), B4DH74 (B4DH74_HUMAN)
Relationships Total Number of functionally related compound(s) : 49
Total Number of Articles : 31
Description

carbohydrate sulfotransferase 15

Gene Summary

Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

synonyms
  • carbohydrate sulfotransferase 15
  • B cell RAG associated protein (GALNAC4S-6ST)
  • B-cell RAG-associated gene protein
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Properties