| Protein Name | ryanodine receptor 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 689560 |
| Gene Symbol | Ryr2 |
| UniProt | B0LPN4 (RYR2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
235
Total Number of Articles : 306 |
Description |
ryanodine receptor 2 |
| Gene Summary |
Enables ryanodine-sensitive calcium-release channel activity and scaffold protein binding activity. Involved in several processes, including metal ion transport; regulation of cytosolic calcium ion concentration; and response to magnesium ion. Located in several cellular components, including sarcolemma; sarcomere; and sarcoplasmic reticulum membrane. Is extrinsic component of cytoplasmic side of plasma membrane. Part of protein-containing complex. Used to study congestive heart failure. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy and catecholaminergic polymorphic ventricular tachycardia 1. Orthologous to human RYR2 (ryanodine receptor 2). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |