Protein Name adenylate cyclase activating polypeptide 1
Organism Rattus norvegicus
Gene ID 24166
Gene Symbol

Adcyap1

UniProt P13589 (PACA_RAT)
Relationships Total Number of functionally related compound(s) : 333
Total Number of Articles : 514
Description

adenylate cyclase activating polypeptide 1

Gene Summary

Enables neuropeptide hormone activity; pituitary adenylate cyclase activating polypeptide activity; and pituitary adenylate cyclase-activating polypeptide receptor binding activity. Involved in several processes, including negative regulation of acute inflammatory response; positive regulation of cell communication; and positive regulation of macromolecule metabolic process. Located in extracellular space and terminal bouton. Is active in neuronal dense core vesicle lumen. Used to study Parkinsonism and acute necrotizing pancreatitis. Biomarker of cystitis. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human ADCYAP1 (adenylate cyclase activating polypeptide 1). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • pituitary adenylate cyclase-activating polypeptide
  • adenylate cyclase activating polypeptide 1 (pituitary)
  • pituitary adenylate cyclase activating polypeptide 1
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Properties