Protein Name | adenylate cyclase activating polypeptide 1 |
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Organism | Rattus norvegicus |
Gene ID | 24166 |
Gene Symbol | Adcyap1 |
UniProt | P13589 (PACA_RAT) |
Relationships |
Total Number of functionally related compound(s) :
333
Total Number of Articles : 514 |
Description |
adenylate cyclase activating polypeptide 1 |
Gene Summary |
Enables neuropeptide hormone activity; pituitary adenylate cyclase activating polypeptide activity; and pituitary adenylate cyclase-activating polypeptide receptor binding activity. Involved in several processes, including negative regulation of acute inflammatory response; positive regulation of cell communication; and positive regulation of macromolecule metabolic process. Located in extracellular space and terminal bouton. Is active in neuronal dense core vesicle lumen. Used to study Parkinsonism and acute necrotizing pancreatitis. Biomarker of cystitis. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human ADCYAP1 (adenylate cyclase activating polypeptide 1). [provided by Alliance of Genome Resources, May 2025] |
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