Protein Name CD6 molecule
Organism Homo sapiens
Gene ID 923
Gene Symbol

CD6

UniProt P30203 (CD6_HUMAN), Q6AZ88 (Q6AZ88_HUMAN), Q8N4Q7 (Q8N4Q7_HUMAN)
Relationships Total Number of functionally related compound(s) : 141
Total Number of Articles : 140
Description

CD6 molecule

Gene Summary

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

synonyms
  • T-cell differentiation antigen CD6
  • CD6 antigen
  • T12
Click to show/hide the synonyms
Properties