Protein Name diacylglycerol kinase alpha
Organism Homo sapiens
Gene ID 1606
Gene Symbol

DGKA

UniProt P23743 (DGKA_HUMAN), A0A024RB23 (A0A024RB23_HUMAN)
Relationships Total Number of functionally related compound(s) : 71
Total Number of Articles : 74
Description

diacylglycerol kinase alpha

Gene Summary

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Apr 2017]

synonyms
  • diacylglycerol kinase alpha
  • 80 kDa diacylglycerol kinase
  • DAG kinase alpha
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Properties