| Protein Name | peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 23988 |
| Gene Symbol | Pin1 |
| UniProt | Q9QUR7 (PIN1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
90
Total Number of Articles : 103 |
Description |
peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 |
| Gene Summary |
Enables several functions, including beta-catenin binding activity; peptidyl-prolyl cis-trans isomerase activity; and phosphoprotein binding activity. Involved in several processes, including negative regulation of amyloid-beta formation; protein peptidyl-prolyl isomerization; and protein stabilization. Acts upstream of or within regulation of cell population proliferation and regulation of cytokinesis. Located in cytosol and nucleus. Is active in glutamatergic synapse. Is expressed in several structures, including 2-cell stage embryo; gut; nucleus pulposus; and reproductive system. Used to study Alzheimer's disease. Orthologous to human PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1). [provided by Alliance of Genome Resources, May 2025] |
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