Protein Name fos-like antigen 1
Organism Mus musculus
Gene ID 14283
Gene Symbol

Fosl1

UniProt P48755 (FOSL1_MOUSE), Q3UMK5 (Q3UMK5_MOUSE)
Relationships Total Number of functionally related compound(s) : 60
Total Number of Articles : 51
Description

fos-like antigen 1

Gene Summary

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and promoter-specific chromatin binding activity. Acts upstream of or within several processes, including placenta blood vessel development; toll-like receptor signaling pathway; and vitellogenesis. Predicted to be located in nucleoplasm and presynaptic membrane. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including extraembryonic component; genitourinary system; limb mesenchyme; and lung. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human FOSL1 (FOS like 1, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • fos-related antigen 1
  • Fra1
  • fra-1
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Properties