| Protein Name | adrenergic receptor, alpha 2a |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11551 |
| Gene Symbol | Adra2a |
| UniProt | Q01338 (ADA2A_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
100
Total Number of Articles : 155 |
Description |
adrenergic receptor, alpha 2a |
| Gene Summary |
Enables alpha2-adrenergic receptor activity. Involved in negative regulation of insulin secretion and presynaptic modulation of chemical synaptic transmission. Acts upstream of or within G protein-coupled receptor signaling pathway and fear response. Is active in dopaminergic synapse. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb segment; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; attention deficit hyperactivity disorder; familial partial lipodystrophy; nicotine dependence; and type 2 diabetes mellitus. Orthologous to human ADRA2A (adrenoceptor alpha 2A). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |