Protein Name nuclear factor of activated T cells 5
Organism Homo sapiens
Gene ID 10725
Gene Symbol

NFAT5

UniProt O94916 (NFAT5_HUMAN), A0A024R734 (A0A024R734_HUMAN)
Relationships Total Number of functionally related compound(s) : 91
Total Number of Articles : 116
Description

nuclear factor of activated T cells 5

Gene Summary

The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • nuclear factor of activated T-cells 5
  • NFAT-like protein 1
  • T-cell transcription factor NFAT5
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Properties