Protein Name vav 1 oncogene
Organism Mus musculus
Gene ID 22324
Gene Symbol

Vav1

UniProt P27870 (VAV_MOUSE), Q3U9E2 (Q3U9E2_MOUSE), Q8VDU4 (Q8VDU4_MOUSE), E9PXI0 (E9PXI0_MOUSE), Q3UAV5 (Q3UAV5_MOUSE)
Relationships Total Number of functionally related compound(s) : 60
Total Number of Articles : 103
Description

vav 1 oncogene

Gene Summary

Enables guanyl-nucleotide exchange factor activity and phosphorylation-dependent protein binding activity. Acts upstream of or within several processes, including integrin-mediated signaling pathway; neutrophil chemotaxis; and positive regulation of natural killer cell mediated cytotoxicity. Located in cell-cell junction. Is expressed in several structures, including extraembryonic component; hemolymphoid system; liver; pancreas; and trunk mesenchyme. Orthologous to human VAV1 (vav guanine nucleotide exchange factor 1). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • proto-oncogene vav
  • p95vav
  • vav oncogene
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Properties