Protein Name oligodendrocyte transcription factor 2
Organism Mus musculus
Gene ID 50913
Gene Symbol

Olig2

UniProt Q9EQW6 (OLIG2_MOUSE), Q542S0 (Q542S0_MOUSE)
Relationships Total Number of functionally related compound(s) : 62
Total Number of Articles : 63
Description

oligodendrocyte transcription factor 2

Gene Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; HMG box domain binding activity; and identical protein binding activity. Acts upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; nervous system development; and positive regulation of oligodendrocyte differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; epidermis; future brain; genitourinary system; and sensory organ. Orthologous to human OLIG2 (oligodendrocyte transcription factor 2). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • oligodendrocyte transcription factor 2
  • Bhlhb1
  • Olg-2
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Properties