CPRiL

Protein Name	mechanistic Target of rapamycin
Organism	Drosophila melanogaster
Gene ID	47396
Gene Symbol	mTor
UniProt	Q9VK45 (TOR_DROME), H1ZYB5 (H1ZYB5_DROME), M9PFS0 (M9PFS0_DROME)
Relationships	Total Number of functionally related compound(s) : 54 Total Number of Articles : 73
Description	mechanistic Target of rapamycin
Gene Summary	Enables chromatin DNA binding activity and protein kinase activity. Involved in several processes, including cell surface receptor protein tyrosine kinase signaling pathway; negative regulation of catabolic process; and positive regulation of cellular component biogenesis. Located in cytoplasm. Part of TORC1 complex and TORC2 complex. Is expressed in adult head. Human ortholog(s) of this gene implicated in autosomal dominant polycystic kidney disease; kidney angiomyolipoma; lung disease (multiple); prostate cancer; and type 2 diabetes mellitus. Orthologous to human MTOR (mechanistic target of rapamycin kinase). [provided by Alliance of Genome Resources, May 2025]
synonyms	mechanistic target of rapamycin CG5092-PA CG5092-PB Target-of-rapamycin mTOR mTor-PA mTor-PB target of rapamycin target of rapamycin complex 1 target of rapamycin kinase Dmel_CG5092 5092 CG5092 CT16317 CT24745 CT24817 DmTOR Dmel\CG5092 FRAP/TOR MTOR Mtor TOR TOR-C1 TORC1 Tor Tor-C1 Torc1 dTOR dTORC1 dTor Click to show/hide the synonyms
Properties