| Protein Name | mannosyl-oligosaccharide glucosidase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 7841 |
| Gene Symbol | MOGS |
| UniProt | Q13724 (MOGS_HUMAN), Q58F09 (Q58F09_HUMAN), A0A384MDR6 (A0A384MDR6_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
69
Total Number of Articles : 64 |
Description |
mannosyl-oligosaccharide glucosidase |
| Gene Summary |
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
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