| Protein Name | ATP binding cassette subfamily C member 3 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8714 |
| Gene Symbol | ABCC3 |
| UniProt | O15438 (MRP3_HUMAN), Q86VN9 (Q86VN9_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
426
Total Number of Articles : 527 |
Description |
ATP binding cassette subfamily C member 3 |
| Gene Summary |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
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