Protein Name potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Organism Mus musculus
Gene ID 16534
Gene Symbol

Kcnn4

UniProt O89109 (KCNN4_MOUSE)
Relationships Total Number of functionally related compound(s) : 102
Total Number of Articles : 100
Description

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Gene Summary

Enables intermediate conductance calcium-activated potassium channel activity. Involved in potassium ion transmembrane transport. Acts upstream of or within several processes, including cell volume homeostasis; phospholipid translocation; and saliva secretion. Predicted to be located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and cytosol. Predicted to be active in neuron projection; neuronal cell body; and plasma membrane. Is expressed in several structures, including alimentary system; liver; metanephros; nervous system; and skeleton. Human ortholog(s) of this gene implicated in angiosarcoma; cerebral infarction; dehydrated hereditary stomatocytosis 2; hypertension; and myocardial infarction. Orthologous to human KCNN4 (potassium calcium-activated channel subfamily N member 4). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • intermediate conductance calcium-activated potassium channel protein 4
  • SKCa 4
  • SKCa4
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Properties