| Protein Name | solute carrier family 6 member 3 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24898 |
| Gene Symbol | Slc6a3 |
| UniProt | P23977 (SC6A3_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
564
Total Number of Articles : 704 |
Description |
solute carrier family 6 member 3 |
| Gene Summary |
Enables several functions, including amine binding activity; enzyme binding activity; and sodium:chloride symporter activity. Involved in several processes, including dopamine transport; response to cAMP; and response to ethanol. Located in neuron projection and plasma membrane. Is active in dopaminergic synapse; postsynaptic membrane; and presynaptic membrane. Biomarker of Parkinsonism; heroin dependence; high grade glioma; hyperprolactinemia; and hypertension. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; classic dopamine transporter deficiency syndrome; mild cognitive impairment; nicotine dependence; and obesity. Orthologous to human SLC6A3 (solute carrier family 6 member 3). [provided by Alliance of Genome Resources, May 2025] |
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| Properties | |