Protein Name actin, beta
Organism Rattus norvegicus
Gene ID 81822
Gene Symbol

Actb

UniProt P60711 (ACTB_RAT)
Relationships Total Number of functionally related compound(s) : 121
Total Number of Articles : 111
Description

actin, beta

Gene Summary

Enables protein kinase binding activity. Involved in several processes, including cellular response to electrical stimulus; regulation of norepinephrine uptake; and response to immobilization stress. Located in actin cytoskeleton; axon; and membrane raft. Part of protein-containing complex. Used to study metabolic dysfunction-associated steatotic liver disease. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome 1 and thrombocytopenia. Orthologous to human ACTB (actin beta). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • actin, cytoplasmic 1
  • beta-actin
  • cytoplasmic beta-actin
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Properties