Protein Name bone morphogenetic protein receptor type 2
Organism Rattus norvegicus
Gene ID 140590
Gene Symbol

Bmpr2

UniProt F1LQC5 (F1LQC5_RAT)
Relationships Total Number of functionally related compound(s) : 41
Total Number of Articles : 36
Description

bone morphogenetic protein receptor type 2

Gene Summary

Enables growth factor binding activity. Involved in retina development in camera-type eye. Located in several cellular components, including apical plasma membrane; basal plasma membrane; and caveola. Used to study pulmonary hypertension. Biomarker of pulmonary hypertension. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease 1. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • bone morphogenetic protein receptor type-2
  • bone morphogenetic protein receptor type II
  • bone morphogenetic protein receptor, type II (serine/threonine kinase)
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Properties