Protein Name prostaglandin E synthase
Organism Mus musculus
Gene ID 64292
Gene Symbol

Ptges

UniProt Q9JM51 (PTGES_MOUSE), Q8BNP8 (Q8BNP8_MOUSE)
Relationships Total Number of functionally related compound(s) : 448
Total Number of Articles : 755
Description

prostaglandin E synthase

Gene Summary

Enables prostaglandin-D synthase activity and prostaglandin-E synthase activity. Involved in cyclooxygenase pathway; regulation of fever generation; and sensory perception of pain. Acts upstream of or within negative regulation of cell population proliferation; positive regulation of prostaglandin secretion; and prostaglandin metabolic process. Located in endoplasmic reticulum membrane and nuclear envelope lumen. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human PTGES (prostaglandin E synthase). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • prostaglandin E synthase
  • glutathione peroxidase PTGES
  • glutathione transferase PTGES
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Properties