Protein Name | prostaglandin E synthase |
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Organism | Mus musculus |
Gene ID | 64292 |
Gene Symbol | Ptges |
UniProt | Q9JM51 (PTGES_MOUSE), Q8BNP8 (Q8BNP8_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
448
Total Number of Articles : 755 |
Description |
prostaglandin E synthase |
Gene Summary |
Enables prostaglandin-D synthase activity and prostaglandin-E synthase activity. Involved in cyclooxygenase pathway; regulation of fever generation; and sensory perception of pain. Acts upstream of or within negative regulation of cell population proliferation; positive regulation of prostaglandin secretion; and prostaglandin metabolic process. Located in endoplasmic reticulum membrane and nuclear envelope lumen. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human PTGES (prostaglandin E synthase). [provided by Alliance of Genome Resources, May 2025] |
synonyms |
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Properties | |