CPRiL

Abcg8

ATP binding cassette subfamily G member 8

Predicted to enable ATPase-coupled transmembrane transporter activity and protein heterodimerization activity. Predicted to contribute to ATP binding activity; ATP hydrolysis activity; and cholesterol transfer activity. Involved in several processes, including cholesterol homeostasis; response to muscle activity; and triglyceride homeostasis. Predicted to be located in apical plasma membrane. Predicted to be part of ATP-binding activity cassette (ABC) transporter complex and receptor complex. Predicted to be active in plasma membrane. Biomarker of cholestasis and metabolic dysfunction-associated steatotic liver disease. Human ortholog(s) of this gene implicated in arteriosclerosis; familial hyperlipidemia; obesity; sitosterolemia; and sitosterolemia 1. Orthologous to human ABCG8 (ATP binding cassette subfamily G member 8). [provided by Alliance of Genome Resources, May 2025]

• ATP-binding cassette sub-family G member 8
• ATP-binding cassette, sub-family G (WHITE), member 8
• ATP-binding cassette, subfamily G (WHITE), member 8
sterolin 2