| Protein Name | D-amino acid oxidase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1610 |
| Gene Symbol | DAO |
| UniProt | P14920 (OXDA_HUMAN), A0A024RBI1 (A0A024RBI1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
410
Total Number of Articles : 386 |
Description |
D-amino acid oxidase |
| Gene Summary |
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008] |
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