Protein Name glycine N-methyltransferase
Organism Mus musculus
Gene ID 14711
Gene Symbol

Gnmt

UniProt Q9QXF8 (GNMT_MOUSE)
Relationships Total Number of functionally related compound(s) : 38
Total Number of Articles : 39
Description

glycine N-methyltransferase

Gene Summary

Enables glycine N-methyltransferase activity and glycine binding activity. Involved in S-adenosylmethionine metabolic process and protein homotetramerization. Acts upstream of or within several processes, including glycogen metabolic process; one-carbon metabolic process; and regulation of gluconeogenesis. Predicted to be part of methyltransferase complex. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; integumental system; limb; sensory organ; and skeleton. Used to study glycine N-methyltransferase deficiency and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in glycine N-methyltransferase deficiency. Orthologous to human GNMT (glycine N-methyltransferase). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • glycine N-methyltransferase
  • glycine N methyl transferase
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Properties