| Protein Name | AKT serine/threonine kinase 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 208 |
| Gene Symbol | AKT2 |
| UniProt | P31751 (AKT2_HUMAN), B4DG79 (B4DG79_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
193
Total Number of Articles : 244 |
Description |
AKT serine/threonine kinase 2 |
| Gene Summary |
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling. [provided by RefSeq, Nov 2019] |
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