Protein Name cytochrome P450, family 1, subfamily A
Organism Danio rerio
Gene ID 140634
Gene Symbol

cyp1a

UniProt Q8UW07 (Q8UW07_DANRE)
Relationships Total Number of functionally related compound(s) : 106
Total Number of Articles : 114
Description

cytochrome P450, family 1, subfamily A

Gene Summary

Predicted to enable monooxygenase activity. Acts upstream of or within cellular response to xenobiotic stimulus. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including digestive system; pectoral fin bud; pericardial region; tail bud; and vasculature. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); diabetes mellitus (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to several human genes including CYP1A2 (cytochrome P450 family 1 subfamily A member 2). [provided by Alliance of Genome Resources, May 2025]

synonyms
  • cytochrome P450 1A1
  • cytochrome P450, subfamily I, polypeptide 1
  • cyp1a1
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Properties